Subclinical epileptiform activity in the Alzheimer continuum: association with disease, cognition and detection method

Table 2 Prevalence of SEA and IED number in the AD group and healthy controls

	AD group	Healthy controls	P-value
SEA [SEA, as expressed per total amount of dementia/MCI/preclinical AD participants]	15/49 (31%) [4/9/2 / 8/33/8]	2/24 (8%)	0.041
Based upon LTM-EEG	9/48 (19%) [4/4/1 / 8/32/8]	1/23 (4%)	0.151
Based upon hd-EEG	5/26 (19%) [0/5/0 / 2/19/5]	1/13 (8%)	0.643
Based upon MEG	4/16 (25%) [2/1/1 / 3/10/3]	0/7 (0%)	0.273
IED number
Based upon LTM-EEG (median: 23.5 h)	5 [3;8]	4	0.726
Based upon hd-EEG (50 min)	3 [3;4]	2	0.221
Based upon MEG (50 min)	64.5 [7.75;131.5]	0	N/A

Data is reported as number or median with IQR [Q1,Q3], as appropriate. P-values were calculated with Fisher’s exact and Mann–Whitney U test. Significance level was set at 0.05. Spike number based upon MEG could not be compared between the AD group and healthy controls, as no spikes were found in the healthy control group, therefore this is not applicable (N/A)

ISSN: 1758-9193