From: Multimodal lifestyle engagement patterns support cognitive stability beyond neuropathological burden
Mean (SD) or N (%) | ||
---|---|---|
Demographics | ||
Baseline age | 79.75 (7.55) | |
Education | 14.91 (3.31) | |
Sex (female) | 1537 (75%) | |
Race/ethnicity | ||
White | 1922 (93%) | |
Black/African American | 109 (5%) | |
Other | 28 (2%) | |
Study characteristics | ||
Number of visits | 7.03 (4.69) [range = 1–22] | |
Total time in study until death (n = 791) | 7.61 (4.32) | |
Lifestyle characteristics | ||
Average physical activity raw score | 2.07 (1.15) | |
Average sleep quality raw score | 10.18 (2.46) | |
Average life space raw score | 5.15 (1.00) | |
Average cognitive activities raw score | 3.03 (0.64) | |
Average social activities raw score | 2.48 (0.53) | |
Average social network raw score | 6.66 (4.63) | |
Cognitive characteristics | ||
Baseline global cognition | 0.08 (0.55) | |
Clinical diagnosis | Baseline | Last visit |
Normal cognition | 1510 (73%) | 1130 (55%) |
MCI | 549 (27%) | 492 (24%) |
Dementia | - | 437 (21%) |
Neuropathology (n = 791) | ||
Alzheimer’s disease | 0.71 (0.61) | |
Cerebrovascular disease | 5.46 (3.02) | |
Lewy body disease (present) | 176 (23%) | |
Hippocampal sclerosis/TDP-43 | 0.61 (0.63) |