Table 2 Demographic characteristics and comorbidities of the patients with AD and mixed dementia
Total cohort (n = 15,586) | Statin users (n = 10,869) | Non-users of statins (n = 4717) | p-value | |
|---|---|---|---|---|
Age at baseline | 79.5 (6.8) | 78.7 (6.7) | 80.7 (6.9) | <0.001 |
Women | 9229 (59.2) | 6092 (56.0) | 3137 (66.5) | <0.001 |
Living arrangements | <0.001 | |||
With another adult | 8395 (53.9) | 6230 (57.3) | 2165 (45.9) | |
Alone | 6344 (40.7) | 4123 (38.0) | 2219 (47.0) | |
Nursing home | 777 (5.0) | 466 (4.3) | 311 (6.6) | |
Type of dementia diagnostic unit | 0.36 | |||
Special memory clinic | 10,730 (68.8) | 7507 (69.1) | 3223 (68.3) | |
Primary care | 4856 (31.2) | 3362 (30.9) | 1494 (31.7) | |
MMSE score at baseline | 21.2 (4.8) | 21.3 (4.8) | 20.8 (4.8) | <0.001 |
Diabetes mellitus | 3797 (24.4) | 2922 (26.9) | 875 (18.5) | <0.001 |
Arrhythmia | 529 (3.4) | 356 (3.3) | 173 (3.7) | 0.21 |
Atrial fibrillation | 2129 (13.7) | 1488 (13.7) | 641 (13.6) | 0.87 |
Alcohol-related disorders | 198 (1.3) | 134 (1.2) | 64 (1.4) | 0.53 |
Cardiovascular disease | 3739 (24.0) | 2904 (26.7) | 835 (17.7) | <0.001 |
Heart failure | 1330 (8.5) | 940 (8.6) | 390 (8.3) | 0.43 |
Myocardial infarction | 1921 (12.3) | 1480 (13.6) | 441 (9.3) | <0.001 |
Ischemic heart disease | 4300 (21.8) | 2551 (23.5) | 849 (18.0) | <0.001 |
Respiratory disease | 995 (6.4) | 681 (6.3) | 314 (6.7) | 0.36 |
Haemorrhagic stroke | 196 (1.3) | 149 (1.4) | 47 (1.0) | 0.05 |
Other stroke types | 1523 (9.8) | 1164 (10.7) | 359 (7.6) | <0.001 |
Anaemia | 508 (3.3) | 335 (3.1) | 173 (3.7) | 0.06 |
Hypertension | 6244 (40.1) | 4428 (40.7) | 1816 (38.5) | 0.01 |
Malignancy | 3784 (24.3) | 2585 (23.8) | 1199 (25.4) | 0.03 |
Liver disease | 71 (0.5) | 35 (0.3) | 26 (0.8) | <0.001 |
Obesity | 179 (1.1) | 139 (1.3) | 40 (0.8) | 0.02 |
Renal disease | 447 (2.9) | 323 (3.0) | 124 (2.6) | 0.24 |