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Table 3 Tests and scores included in the Neuropsychological Test Battery conducted for Primary/Cognitive outcomes assessment

From: A multimodal precision-prevention approach combining lifestyle intervention with metformin repurposing to prevent cognitive impairment and disability: the MET-FINGER randomised controlled trial protocol

Cognitive test

Item/score included

Relevant cognitive domain

WMSR—Logical Memory

Immediate recall

Memory

WMSR—Logical Memory

Delayed recall

Memory

WMSR—Visual Paired Associates

Immediate recall

Memory

WMSR—Visual Paired Associates

Delayed recall

Memory

HVLT

Learning score

Memory

HVLT

Delayed recall score

Memory

Digit Span

Maximum correct span

Executive functioning

CERAD Category Fluency

Number of correct animals mentioned

Executive functioning

Category Fluency II

Number of correct fruits/vegetables mentioned

Executive functioning

TMT

Score A

Processing speed

TMT

Shifting score B-A

Executive functioning

Stroop

Condition 2

Processing speed

Stroop

Interference score condition 3 -2

Executive functioning

WAIS-DSST

Total score

Processing speed

  1. The bibliography for assessment tools, tests, and scales used in the trial is presented in Supplementary Table 1
  2. CERAD Consortium to Establish a Registry for Alzheimer’s Disease, DSST Digit-Symbol Substitution Test, HVLT Hopkins Verbal Learning Test, TMT Trail Making Test, WAIS Wechsler Adult Intelligence Scale, WMSR Wechsler Memory Scale Revised