Fig. 2

Plasma biomarker values in the A − / + , AD − / + , and ATN groups. The figure shows the box and whiskers plots of plasma markers by groups. The abscissa axis represents the different groups according to the CSF (amyloid status in the first row, AD status in the second one, and ATN group in the third one). The ordinate axis corresponds to plasma concentrations expressed in pg/ml (where applicable). The boxes show the interquartile range (the upper boundary is the Q3, and the lower boundary is the Q1). The line inside the box corresponds to the median of the sample, and the whiskers represent the maximum (upper) and minimum (lower) values. The dots indicate individual values. Significant differences are indicated with a horizontal line and three asterisks between the boxes. Abbreviations: AD, Alzheimer’s disease; A, amyloid; Aβ, amyloid beta; P-tau, phosphorylated tau; T, tau; N, neurodegeneration