Fig. 1
From: Neuron-derived extracellular vesicles in blood reveal effects of exercise in Alzheimer’s disease
Neurotrophic and neuroprotective factors carried by NDEVs increase after exercise. Bar graphs show the concentrations of proBDNF (A), BDNF (B), and humanin (C) in NDEVs of control and exercise group participants at baseline (light blue) and 16 weeks (dark blue). D Humanin in EVs of all cellular origins immunocaptured by targeting panTET-EVs. Graphs show the estimated marginal mean ± standard error of the mean from repeated measures mixed-effects models. * indicates p < 0.05; ns: not significant