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Table 1 Baseline participant characteristics according to walking status

From: High-intensity walking in midlife is associated with improved memory in physically capable older adults

 

Overall

Non-walking

Walking

p

n

188

63

125

 

Age, years

72.01 (5.16)

72.67 (5.23)

71.67 (5.11)

0.213a

Female, no. (%)

133 (70.74)

45 (71.43)

88 (70.40)

0.884b

Education, no. (%)

   

0.197b

 ≥13 years

39 (20.74)

9 (14.29)

30 (24.00)

 

 10–12 years

50 (26.60)

14 (22.22)

36 (28.80)

 

 4–9 years

82 (43.62)

33 (52.38)

49 (39.20)

 

 0–3 years

17 (9.04)

7 (11.11)

10 (8.00)

 

MMSE

25.67 (3.42)

24.76 (3.80)

26.13 (3.14)

0.009a

APOE4 positivity, no. (%)

37 (19.68)

13 (20.63)

24 (19.20)

0.815b

Clinical diagnosis, CN, no. (%)

107 (56.91)

33 (52.38)

74 (59.20)

0.373b

Walking intensity

   

< 0.001b

 None

63 (33.51)

63 (100.00)

0 (0.00)

 

 Low (less than moderate-intensity)

68 (4.93)

0 (0.00)

68 (54.40)

 

 High (moderate to vigorous-intensity)

57 (30.32)

0 (0.00)

57 (45.60)

 

Walking duration

   

< 0.001b

 None

63 (33.51)

63 (100.00)

0 (0.00)

 

 Low (6 h or less per week)

75 (39.89)

0 (0.00)

75 (60.00)

 

 High (more than 6 h per week)

50 (26.60)

0 (0.00)

50 (40.00)

 

Number of years of walking practice

   

< 0.001a

 Midlife (40–64 years)

18.18 (13.37)

0 (0.00)

18.18 (13.37)

 

 Late life (≥65 years)

4.95 (6.28)

0 (0.00)

4.95 (6.28)

 

 Overall

9.98 (13.02)

0 (0.00)

15.43 (13.35)

 

Walking onset

   

< 0.001b

 Midlife (40−64 years)

103 (54.79)

0 (0.00)

103 (82.40)

 

 Late life (≥65 years)

22 (11.70)

0 (0.00)

22 (17.60)

 

Annual income, no. (%)

 < MCL

23 (12.23)

9 (14.29)

14 (11.20)

0.371b

 ≥ MCL, < 2×MCL

59 (31.38)

23 (36.51)

36 (28.80)

 

 ≥ 2×MCL

106 (56.38)

31 (49.21)

75 (60.00)

 

VRS, %

23.85 (18.57)

25.40 (17.67)

23.07 (19.02)

0.418a

GDS, no. (%)

   

0.572b

  Normal (< 9)

92 (48.94)

29 (46.03)

63 (50.40)

 

  Depressed (≥10)

96 (51.06)

34 (53.97)

62 (49.60)

 

UPDRS, gait disturbance requiring assistance

0 (0.00)

0 (0.00)

0 (0.00)

 

Body mass index

  Underweight (< 18.5)

4 (2.13)

0 (0.00)

4 (3.20)

0.131c

  Normal weight (18.5–24.9)

95 (50.53)

28 (44.44)

67 (53.60)

 

  Overweight (≥ 25)

89 (47.34)

35 (55.56)

54 (43.20)

 

Alcohol drink status, no (%)

   

0.846b

  Never

105 (55.85)

35 (55.56)

70 (56.00)

 

  Former

32 (17.02)

12 (19.05)

20 (16.00)

 

  Drinker

51 (27.13)

16 (25.40)

35 (28.00)

 

PASE total score

65.56 (46.58)

70.73 954.79)

62.96 (41.84)

0.281a

Blood markers

 Hemoglobin

13.33 (1.52)

13.25 (1.60)

13.37 (1.49)

0.592a

 Albumin

4.57 (0.26)

4.57 (0.26)

4.58 (0.26)

0.906a

 Glucose, fasting

108.40 (20.31)

108.34 (17.76)

108.44 (21.54)

0.976a

 HDL-cholesterol

54.87 (12.90)

53.58 (13.61)

55.52 (12.54)

0.336a

 LDL-cholesterol

96.13 (33.40)

98.21 (34.64)

95.10 (32.85)

0.550a

Nutritional markers

 Protein, no (%)

   

0.390b

  High

25 (13.30)

6 (9.52)

19 (15.20)

 

  Moderate

73 (38.83)

23 (36.51)

50 (40.00)

 

  Low

90 (47.87)

34 (53.97)

56 (44.80)

 

 Fruit and vegetables, no (%)

   

0.972b

  High

128 (68.09)

43 (68.25)

85 (68.00)

 

  Low

60 (31.91)

20 (31.75)

40 (32.00)

 

Decrease in food intake over the past 3 months, no (%)

14 (7.45)

6 (9.52)

8 (6.40)

0.557c

CERAD cognition

 Total score

70.50 (15.47)

65.21 (14.48)

73.17 (15.32)

< 0.001a

 Memory score

35.45 (9.31)

32.56 (9.62)

36.91 (8.83)

0.002a

 Non-memory score

34.39 (6.64)

33.05 (6.56)

35.07 (6.59)

0.048a

  1. Data are expressed as mean (standard deviation), unless otherwise indicated
  2. MMSE mini-mental status examination, APOE4 apolipoprotein ε4, CN cognitively normal, MCL minimum cost of living, VRS vascular risk score, GDS geriatric depression scale, UPDRS Unified Parkinson’s Disease Rating Scale, PASE physical activity scale for the elderly, CERAD Consortium to Establish a Registry for Alzheimer’s Disease
  3. aBy Student t-test
  4. bBy chi-square test
  5. cBy Fisher exact test