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Table 3 Results of multivariate regression analysis exploring the odds of having pathological values of p-tau/Aβ42 in A + T − patients

From: Different associations between amyloid-βeta 42, amyloid-βeta 40, and amyloid-βeta 42/40 with soluble phosphorylated-tau and disease burden in Alzheimer’s disease: a cerebrospinal fluid and fluorodeoxyglucose-positron emission tomography study

 

p-tau/Aβ42 cut-off ≥ 0.086

p-tau/Aβ42 cut-off ≥ 0.122

 

Odds ratio (CI)

p

Odds ratio (CI)

p

amyR

23.27 (6.47–83.60)

 < 0.001

8.82 (3.28–23.68)

 < 0.001

Diabetes

0.38 (0.11–1.32)

0.13

0.51 (0.19–1.40)

0.19

Hypertension

0.99 (0.26–3.72)

0.99

1.25 (0.39–4.03)

0.71

Dyslipidemia

2.79 (0.71–10.95)

0.14

1.09 (0.34–3.47)

0.88

APOE4

5.93 (1.61–21.79)

0.007

1.27 (0.45–3.58)

0.65

Age

1.07 (0.99–1.14)

0.06

1.02 (0.96–1.07)

0.48

Sex

1.31 (0.43–4.03)

0.63

1.82 (0.68–4.91)

0.23

  1. Bold values represent p-value < 0.05
  2. amyR42/Aβ40, CI 95% confidence interval, p p-value