Skip to main content
Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Feasibility and therapeutical potential of local intracerebral encapsulated cell biodelivery of BDNF to AppNL−G−F knock-in Alzheimer mice

Fig. 2

Design of miniaturized ECB device, in vitro BDNF release quantification and ex vivo immune response. A Representative picture of a miniaturized ECB device. B BDNF release (ng/mL/24 h) from three independent ECB-BDNF devices (black, red, and blue symbols) were monitored for 7 weeks, where BDNF levels were measured by ELISA. C Representative dot plots and D, E bar diagram, depicts the TNF-⍺ positivity among the B and T cells in splenocytes isolated from WT mice which were incubated with different ECB devices for 48 h and examined by flow cytometry (n = 3). Data are represented as mean ± S.E.M. and analyzed by unpaired Student’s t-test

Back to article page

Alzheimer's Research & Therapy

ISSN: 1758-9193