Table 1 Baseline demographics and characteristics

N (%)

581 (100.0)

334 (57.5)

247 (42.5)

Age in years

73.9 ± 7.6

72.9 ± 7.2

75.1 ± 8.0

 < 0.001

Female, n (%)

304 (52.3)

201 (60.2)

103 (41.7)

 < 0.001

Years of education

16.5 ± 2.5

16.7 ± 2.3

16.1 ± 2.7

0.024

Race, n (%)

0.220

 White

534 (91.9)

300 (89.9)

234 (94.7)

 Black, African American

25 (4.3)

18 (5.4)

7 (2.8)

 Asian

8 (1.4)

6 (1.8)

2 (0.8)

 American Indian, Alaskan Native

2 (0.3)

2 (0.6)

0 (0.0)

 Multiracial

11 (1.9)

8 (2.4)

3 (1.2)

Hispanic/Latino Ethnicity, n (%)

27 (4.6)

19 (5.7)

8 (3.2)

0.164

Baseline FAQ

2.4 ± 5.0

0.2 ± 0.9

5.3 ± 6.6

 < 0.001

MMSE

28.2 ± 2.3

29.1 ± 1.2

27.0 ± 2.8

 < 0.001

AmNART VIQ

119.9 ± 10.9

121.7 ± 10.3

117.4 ± 11.3

 < 0.001

Amyloid-PET

 Centiloids

32.1 ± 40.8

23.3 ± 31.7

44.3 ± 48.1

 < 0.001

 Positive, n (%)

259 (44.6)

125 (37.4)

134 (54.3)

 < 0.001

Tau-PET

 Entorhinal

1.22 ± 0.22

1.15 ± 0.13

1.32 ± 0.28

 < 0.001

 Inferior temporal

1.29 ± 0.27

1.22 ± 0.14

1.38 ± 0.36

 < 0.001

 Precuneus

1.17 ± 0.21

1.12 ± 0.10

1.23 ± 0.29

 < 0.001

 Posterior cingulate

1.14 ± 0.17

1.11 ± 0.10

1.18 ± 0.23

 < 0.001

 Supramarginal

1.12 ± 0.17

1.09 ± 0.10

1.17 ± 0.23

 < 0.001

 DLPF

1.07 ± 0.17

1.04 ± 0.09

1.11 ± 0.24

0.002

Follow-up duration in years

2.5 ± 1.2

2.6 ± 1.0

2.5 ± 1.3

0.067