Table 3 Multiple linear regressions between REM sleep characteristics and basal forebrain volume in subsamples stratified by cognitive status
From: REM sleep is associated with the volume of the cholinergic basal forebrain in aMCI individuals
Dependent Variable | Independent variables | Unstandardized coefficient (95% CI) | Standard Error | Standardized coefficient | Punc | PFDR-corrected |
|---|---|---|---|---|---|---|
Cognitively unimpaired participants | ||||||
 Ch1-2–3 volume | REM-S percentage | -0.19 (-1.13 – 0.75) | 0.46 | -0.06 | 0.68 |  |
REM-S latency | -16.68 (-37.39 – 4.04) | 10.08 | -0.21 | 0.11 |  | |
REM-S efficiency | -0.31 (-0.7 – 0.09) | 0.19 | -0.22 | 0.12 |  | |
 Ch4 volume | REM-S percentage | 5.4e−4 (-0.002 – 0.003) | 0.001 | 0.07 | 0.70 |  |
REM-S latency | -0.06 (-0.12 – 0.005) | 0.03 | -0.28 | 0.07 |  | |
REM-S efficiency | -9.3e−5 (-0.001 – 0.001) | 6.2e−4 | -0.03 | 0.88 |  | |
 Total BF volume | REM-S percentage | 0.19 (-2.05 – 2.43) | 1.09 | 0.03 | 0.86 |  |
REM-S latency | -52.17 (-99.75 – -4.59) | 23.15 | -0.29 | 0.03 | 0.09 | |
REM-S efficiency | -0.38 (-1.36 – 0.6) | 0.48 | -0.12 | 0.43 |  | |
aMCI participants | ||||||
 Ch1-2–3 volume | REM-S percentage | 0.68 (-0.63 – 1.99) | 0.64 | 0.19 | 0.3 |  |
REM-S latency | 1.69 (-20.62 – 24) | 10.85 | 0.03 | 0.88 |  | |
REM-S efficiency | 0.15 (-0.38 – 0.69) | 0.26 | 0.1 | 0.56 |  | |
 Ch4 volume | REM-S percentage | 0.006 (0.001 – 0.01) | 0.002 | 0.48 | 0.012 | 0.036 |
REM-S latency | -0.02 (-0.11 – 0.06) | 0.04 | -0.11 | 0.55 |  | |
REM-S efficiency | 7.5e−5 (-0.001 – 0.003) | 9.5e−4 | 0.15 | 0.44 |  | |
 Total BF volume | REM-S percentage | 4.31 (0.93 – 7.68) | 1.64 | 0.44 | 0.014 | 0.042 |
REM-S latency | -14.4 (-77.61 – 48.81) | 30.75 | -0.08 | 0.64 |  | |
REM-S efficiency | 0.54 (-0.99 – 2.06) | 0.74 | 0.14 | 0.48 |  | |