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Table 2 Plasma lipid levels

From: Plasma apolipoprotein E levels, isoform composition, and dimer profile in relation to plasma lipids in racially diverse patients with Alzheimer’s disease and mild cognitive impairment

Race/ethnicity

Diagnosis

TGs (mmol/L)

t-Ch (mmol/L)

LDL (mmol/L)

HDL (mmol/L)

LDL/HDL

Whole cohort (n = 125)

Controls (n = 53)

1.17 ± 0.61

4.71 ± 0.85

2.70 ± 0.78

1.49 ± 0.45

1.97 ± 0.77

MCI (n = 48)

1.12 ± 0.40

4.60 ± 0.87

2.66 ± 0.80

1.46 ± 0.41

1.96 ± 0.83

AD (n = 24)

1.22 ± 0.53

5.36 ± 1.16*,**

3.09 ± 0.81

1.73 ± 0.66

1.96 ± 0.79

p-value

a

0.004a

a

a

a

B/AAs (n = 58)

Controls (n = 25)

1.24 ± 0.57

4.79 ± 0.91

2.81 ± 0.81

1.41 ± 0.38

2.12 ± 0.83

MCI (n = 24)

1.00 ± 0.27

4.52 ± 0.90

2.66 ± 0.92

1.42 ± 0.42

2.07 ± 1.03

AD (n = 9)

1.13 ± 0.44

5.43 ± 1.36

3.19 ± 0.68

1.74 ± 0.79

1.98 ± 0.58

p-value

a

a

a

a

a

NHWs (n = 67)

Controls (n = 28)

1.11 ± 0.66

4.64 ± 0.80

2.60 ± 0.74

1.55 ± 0.50

1.83 ± 0.70

MCI (n = 24)

1.23 ± 0.48

4.69 ± 0.86

2.65 ± 0.68

1.50 ± 0.41

1.85 ± 0.58

AD (n = 15)

1.27 ± 0.59

5.31 ± 1.07

3.03 ± 0.90

1.71 ± 0.61

1.95 ± 0.91

p-value

a

0.049a

a

a

b

  1. Values are represented as average ± standard deviation. p-values were obtained after comparisons between the diagnostic groups using aANOVA or bKruskal-Wallis. “–”: non-significant. *p ≤ 0.05 correspond to the comparison between AD patients and controls (95% CI: 0.11, 1.19), whereas **p ≤ 0.01 refers to the comparison between AD and MCI patients (95% CI: 0.21, 1.30) and acquired using the Tukey HSD test
  2. B/AAs Black/African-Americans, NHWs Non-Hispanic whites, MCI Patients with mild cognitive impairment, AD Patients with Alzheimer’s disease, TGs Triglycerides, t-Ch. Total cholesterol, LDL Low-density lipoprotein, HDL High-density lipoprotein