Fig. 2From: Plasma apolipoprotein E levels, isoform composition, and dimer profile in relation to plasma lipids in racially diverse patients with Alzheimer’s disease and mild cognitive impairmentDistribution of APOE isoforms in the plasma. ApoE plasma isoform composition as a percentage of total apoE (a), plasma concentrations (b–d) of apoE2 (black dots), apoE3 (black triangles), and apoE4 (black squares) in APOE ε2/ε3 (b), APOE ε2/ε4 (c), and APOE ε3/ε4 (d) subjects. Data is presented % (a) and as medians- with lower and upper quartiles and whiskers indicating the data range (b-d). p-values illustrated in b and c were obtained using the Student’s t-test, whereas in d, both the Mann–Whitney U-test for the comparison in the combined races/ethnicities and Student’s t-test for the comparison in Black/African-Americans (B/AAs) and non-Hispanic whites (NHWs) were utilized. Comparison between apoE2 and apoE4 isoforms in APOE ε2/ε4 NHW could not be performed due to the low sample number (n = 1)Back to article page