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Table 1 Demographic and clinical profile of the groups (mean ± SD)

From: Acrolein adducts and responding autoantibodies correlate with metabolic disturbance in Alzheimer’s disease

 

HC

(n = 84)

MetS

(n = 58)

AD-N

(n = 34)

AD-M

(n = 83)

Reference intervala

Gender (female:male)

45:39

21:37

17:17

43:40

-

Age (year)

74.8 ± 4.9

76.3 ± 5.8

81.3 ± 5.4

82.0 ± 6.8

-

ALT (IU/L)

21 ± 15

27 ± 17

17 ± 7

23 ± 18

< 41

Creatinine (mg/dL)

1.0 ± 0.4

1.0 ± 0.5

1.0 ± 0.3

1.5b ± 1.4

0.6—1.2 (53 – 106 µmol/L)

Fasting glucose (mg/dL)

87 ± 9

115 b ± 34

92 ± 6

128b ± 42

70 – 99 (3.9 – 5.5 mmol/L)

HbA1c (%)

5.7 ± 0.1

6.4 b ± 1.1

5.6 ± 0.3

6.3b ± 0.9

4—6

HDL-C (mg/dL)

62 ± 22

55 ± 16

70 ± 27

41 ± 15

> 40 (> 1.04 mmol/L)

LDL-C (mg/dL)

107 ± 27

118 ± 32

111 ± 24

100 ± 29

< 130 (< 3.37 mmol/L)

Total cholesterol (mg/dL)

171 ± 37

190 ± 37

188 ± 34

177 ± 42

< 200 (< 5.18 mmol/L)

Total protein (g/L)

72 ± 17

78 ± 23

73 ± 20

75 ± 26

66 – 87

Triglycerides (mg/dL)

101 ± 24

135 ± 60

88 ± 31

145 ± 79

< 150 (< 1.69 mmol/L)

  1. AD-M Alzheimer’s disease with metabolic syndrome, AD-N Alzheimer’s disease with normal metabolism, HbA1c glycohemoglobin A1, HC healthy control, HDL-C high-density lipoprotein-cholesterol, LDL-C low-density lipoprotein-cholesterol, MetS metabolic syndrome
  2. aThe International System of Units (SI) of reference interval were shown in brackets
  3. bThe mean values exceeding reference intervals were shown in bold