White matter hyperintensities and smaller cortical thickness are associated with neuropsychiatric symptoms in neurodegenerative and cerebrovascular diseases

Table 5 Psychotic subsyndrome analyses

	1000 (70/500)	0.0692 (22/500)	0.0724 (29/500)	0.0631 (35/500)	0.0832 (23/500)	0.0575 (32/500)	0.0661 (28/500)	0.0603 (31/500)
(Intercept)	0.757	3.505	3.254	3.974	2.455	4.402	3.745	4.193
Age	0	− 0.010	− 0.009	− 0.011	− 0.007	− 0.012	− 0.010	− 0.012
Sex(female)	0	− 0.209	− 0.200	− 0.226	− 0.172	− 0.241	− 0.217	− 0.233
MoCA TOTAL	0	− 0.006	− 0.005	− 0.008	− 0.001	− 0.009	− 0.007	− 0.009
LH PARS-ORBITALIS THICKNESS	0	0.153	0.111	0.230	0.000	0.302	0.192	0.267
LH POSTERIOR CINGULATE THICKNESS	0	− 0.040	− 0.031	− 0.056	0.000	− 0.071	− 0.048	− 0.064
LH PRECUNEUS THICKNESS	0	− 0.115	− 0.091	− 0.160	− 0.019	− 0.201	− 0.138	− 0.181
RH CAUDAL ANTERIOR CINGULATE THICKNESS	0	− 0.021	− 0.008	− 0.045	− 0.000	− 0.066	− 0.033	− 0.056
RH ISTHMUS CINGULATE THICKNESS	0	− 0.090	− 0.082	− 0.104	− 0.048	− 0.118	− 0.097	− 0.111
RH PARS-TRIANGULARIS THICKNESS	0	− 0.292	− 0.258	− 0.356	− 0.155	− 0.414	− 0.325	− 0.386
RBGT WMH	0	0.116	0.104	0.129	0.075	0.144	0.121	0.137

Row names indicate variables selected, column names indicate the lambda parameter and how many times out of 500 repeats that the lambda parameter had the lowest mean square error for our repeated cross-validation. Values in the cells are coefficients from the full data sample for the corresponding selected variables (rows) under the penalisation parameter (columns)
MoCA Montreal Cognitive Assessment, LH Left hemisphere, RBGT WMH Right basal ganglia/thalamus white matter hyperintensities, RH Right hemisphere

ISSN: 1758-9193