Fig. 3

Correlation between global network measures with amyloid and tau pathology. Correlation plots showing the linear models with the significant relationships between the clustering coefficient and global efficiency with global Aβ PET SUVR values (a, b) and tau Braak SUVR (c, d) values, while controlling for age, sex, education, and cognitive status. To account for the nonlinear relationships, the squares of the network measures were also included in the model. The gray areas show the 95% confidence intervals (CI) for the predictions, whereas the dashed lines show the best model fit. The dots correspond to show CN Aβ + (blue), MCI Aβ + (light green), and AD Aβ + (dark green) subjects. All results were corrected for multiple comparisons using FDR