Fig. 2

Correlation of plasma Aβ38, Aβ40, and Aβ42 with each other and other variables. Spearman correlation coefficients are stated. *A significant correlation (p < 0.05). A Correlation of plasma Aβ38, Aβ40, and Aβ42 with age, MMSE, other plasma Aβ peptides, CSF Aβ peptides, and number of strictly lobar microbleeds in the patients with D-CAA and controls of the discovery cohort. The correlation with MMSE and number of strictly lobar microbleeds was calculated in the patients with D-CAA only. MMSE (n = 34), CSF Aβ peptides (n = 21), and number of strictly lobar microbleeds (n = 23) were only available for a subset of patients. B Correlation of plasma Aβ38, Aβ40, and Aβ42 with age, MOCA, other plasma Aβ peptides, CSF Aβ peptides, number of strictly lobar microbleeds, Fazekas score, and small vessel disease burden score in the patients with D-CAA and controls of the validation cohort. The correlation with MOCA, CSF Aβ peptides, number of strictly lobar microbleeds, Fazekas score, and small vessel disease burden score was calculated in the patients with D-CAA only. MOCA (n = 56), CSF Aβ38 and Aβ42 (n = 22), CSF Aβ40 (n = 21), and number of strictly lobar microbleeds (n = 50), Fazekas score (n = 50), and small vessel disease burden score (n = 50) were only available for a subset of patients. C Correlation of plasma Aβ38, Aβ40, and Aβ42 with age, MOCA, other plasma Aβ peptides, CSF Aβ peptides, number of strictly lobar microbleeds, Fazekas score, and small vessel disease burden score in the patients with sCAA and controls. MOCA (n = 56), CSF Aβ peptides (n = 16 for CSF Aβ38, n = 30 for CSF Aβ40 and CSF Aβ42), and number of strictly lobar microbleeds (n = 57), Fazekas score (n = 59), and small vessel disease burden score (n = 57) were only available for a subset of patients. Abbreviations: CSF, cerebrospinal fluid; Aβ, amyloid beta; MOCA, Montreal Cognitive Assessment; SVD score, small vessel disease burden score