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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Longitudinal APOE4- and amyloid-dependent changes in the blood transcriptome in cognitively intact older adults

Fig. 5

Module preservation and consensus of baseline or follow-up co-expression modules. Zsummary scores of A baseline WGCNA modules in follow-up expression data and B follow-up co-expression modules in baseline expression data. A Zsummary < 2 suggests low preservation (below blue dotted line); > 2 Zsummary < 10 suggests moderate preservation; Zsummary > 10 suggests high preservation (above green dotted line). Correspondence of C baseline set-specific modules or D follow-up set-specific modules with consensus modules. Each row is the set-specific module and each column is a consensus module. The more red the cell, the more significant the Fisher’s exact p-value (encoded by -log(p) signifying the gene overlap. For module labels in plots A and B for the preservation analyses please see y-axes module

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