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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Alzheimer’s disease genetic risk and cognitive reserve in relationship to long-term cognitive trajectories among cognitively normal individuals

Fig. 2

Estimates of longitudinal cognitive change based on APOE genetic status and level of cognitive reserve. Estimated cognitive change (95% CI) shown for APOE genetic status (APOE-ε2, APOE-ε3, APOE-ε4) and high vs. low CR index scores, represented by the 25th and 75th percentiles for illustration purposes. Sample means were used in the estimation of all other covariates. Cognitive change is shown separately for global (top), memory (middle), and executive function (bottom) factor scores based on the full models, as shown in Table 2. The CR index × APOE-ε4 × time interactions were significant for the global and memory factor scores, but not for the executive function factor score

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Alzheimer's Research & Therapy

ISSN: 1758-9193