From: Validation study of “Santé-Cerveau”, a digital tool for early cognitive changes identification
Controls N = 65 (50.39%) | NDG N = 64 (49.61%) | Estimate of the difference ± SE∫ | p‡ | |
---|---|---|---|---|
Demographics | ||||
Age, year sold | 69.91 ± 4.86 | 72.61 ± 6.79 | 0.011* | |
Gender (Female) | 44 (67.69%) | 29 (45.31%) | 0.013* | |
Educational level | ||||
≤ 12 years | 9 (13.85%) | 17 (26.56%) | 0.204 | |
between 13 and 17 years | 32 (49.23%) | 26 (40.62%) | ||
≥ 17 years | 24 (36.92%) | 21 (32.81%) | ||
Delay between SCD-T and reference CN-Battery, months | -0.44 ± 0.80 | 1.12 ± 1.36 | < 0.001* | |
Medical history | ||||
cardiovascular diseases¥ | 5 (7.69%) | 10 (15.62%) | OR: 0.72 ± 0.47 | 0.615 |
hypertension¥ | 15 (23.08%) | 25 (39.06%) | OR: 0.51 ± 0.22 | 0.161 |
diabetes¥ | 2 (3.08%) | 8 (12.50%) | OR: 0.38 ± 0.32 | 0.262 |
depression¥ | 5 (7.69%) | 17 (26.56%) | OR: 0.16 ± 0.09 | 0.001* |
Reference CNB | ||||
HAD | 8.65 ± 4.50 | 12.14 ± 6.60 | MD: -4.57 ± 1.08 | < 0.001* |
MMSE# | 28.95 ± 0.89 | 24.94 ± 2.40 | MD: 1.74 ± 0.14 | < 0.001* |
FAB# | 17.31 ± 0.97 | 14.38 ± 2.43 | MD: 1.79 ± 0.18 | < 0.001* |
FCSRT free recall# | 34.72 ± 5.19 | 10.39 ± 7.97 | MD: 2.23 ± 0.06 | < 0.001* |
FCSRT total recall# | 47.02 ± 1.29 | 25.25 ± 14.07 | MD: 3.94 ± 0.14 | < 0.001* |
TMT A time, seconds | 61.08 ± 42.88 | |||
TMT B time, seconds | 145.71 ± 80.16 | |||
TMT B-A, time, seconds | 98.24 ± 73.06 | |||
SCD-T | ||||
Time to complete SCD-T (minutes) | 21.67 ± 4.77 | 40.74 ± 12.06 | MD: -18.35 ± 1.67 | < 0.001* |
MacNair | 12.42 ± 6.53 | 17.78 ± 7.26 | MD: -6.81 ± 1.26 | < 0.001* |
GDS | 2.05 ± 1.99 | 3.17 ± 3.19 | MD: -1.48 ± 0.49 | 0.003* |
NCT good answers | 32.88 ± 7.55 | 14.75 ± 8.71 | MD: 16.86 ± 1.47 | < 0.001* |
NCT wrong answers | 1.65 ± 1.89 | 3.48 ± 4.62 | MD: -1.08 ± 0.63 | 0.186 |
NCT total answers | 34.52 ± 6.79 | 18.23 ± 8.46 | MD: 15.78 ± 1.36 | < 0.001* |
5-WT total score# | 9.74 ± 0.54 | 6.31 ± 2.34 | MD: 3.11 ± 0.27 | < 0.001* |
5-WT weighted total score# | 18.88 ± 1.55 | 10.88 ± 3.99 | MD: 2.63 ± 0.14 | < 0.001* |
TMT A time, seconds | 26.62 ± 13.13 | 45.61 ± 34.33 | MD: -17.63 ± 4.92 | < 0.001* |
TMT B time, seconds | 52.37 ± 23.14 | 125.42 ± 87.38 | MD: -74.48 ± 12.01 | < 0.001* |
TMT B-A, time, seconds | 25.85 ± 23.21 | 79.83 ± 76.00 | MD: -56.77 ± 10.51 | < 0.001* |
Acceptability | ||||
SUS | 92.23 ± 10.75 | 79.49 ± 18.70 | MD: 11.39 ± 2.80 | < 0.001* |
QCT: successful as person of the same age1(≥ Good)¥ | 40 (61.54%) | 11 (17.19%) | OR: 8.26 ± 3.84 | < 0.001* |
QCT: representative memory/attention2(≥ fairly representative)¥ | 55 (84.62%) | 47 (73.44%) | OR: 1.51 ± 0.73 | 0.395 |
QCT: perception3(≥ Good)¥ | 49 (75.38%) | 31 (48.44%) | OR: 5.23 ± 2.33 | < 0.001* |
QCT: clear instructions4(≥ fairly clear) | 64 (98.46%) | 60 (93.75%) | ND | ND |
QCT: requires no explanation by a third party5 ¥ | 60 (92.31%) | 46 (71.88%) | OR: 4.57 ± 2.61 | 0.005* |