From: The dynamics of biomarkers across the clinical spectrum of Alzheimer’s disease
Clinical state at baseline | ||||
---|---|---|---|---|
CN | MCI | ADem | ||
Number of individuals | ||||
Total | 749 | 910 | 355 | |
Chronological age at baseline (years) | ≤ 70 | 241 | 308 | 85 |
70 < age < 80 | 402 | 423 | 170 | |
> 80 | 106 | 179 | 100 | |
Gender | Women | 413 | 370 | 157 |
Men | 336 | 540 | 198 | |
Years of education | ≤ 16 | 385 | 537 | 247 |
> 16 | 364 | 373 | 108 | |
Genetic background (APOE ε4) | Non-carriers of ε4 allele | 370 | 420 | 114 |
Carriers of 1 ε4 allele | 135 | 337 | 159 | |
Carriers of 2 ε4 alleles | 12 | 92 | 65 | |
Other characteristics (standard deviation of the mean in brackets) | ||||
Average age at baseline (years) | 73.20 (6.17) | 73.04 (7.62) | 75.03 (7.88) | |
Average number of years of education | 16.55 (2.57) | 15.93 (2.82) | 15.24 (2.99) | |
Average time between visits (years) | 1.02 (0.58) | 0.8 (0.38) | 0.64 (0.27) | |
Average follow-up (years) | 3.36 (3.43) | 3.69 (2.62) | 1.38 (0.85) |