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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: LW-AFC, a new formula derived from Liuwei Dihuang decoction, ameliorates behavioral and pathological deterioration via modulating the neuroendocrine-immune system in PrP-hAβPPswe/PS1ΔE9 transgenic mice

Fig. 3

The LW-AFC treatment alleviated neuron loss in the hippocampus of APP/PS1 mice. a Representative Nissl staining images showing Nissl bodies in the CA1 and CA3 regions of the hippocampus in wild-type (WT ) and APP/PS1 (Tgs) mice. Quantification of Nissl bodies in the brain (b), hippocampus (c), CA1 (d), and CA3 (e) regions of hippocampus in WT and Tgs mice by Image Pro Plus 6.0 software. The values are mean ± SEM; n = 11–15. *P < 0.05, ***P < 0.001, versus the WT mouse group by unpaired Student's t test; # P < 0.05, ## P < 0.01, versus the Tgs mouse group by one-way ANOVA analysis followed by Dunnett’s post hoc test. IOD integrated optical density

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Alzheimer's Research & Therapy

ISSN: 1758-9193