Fig. 2
From: Generation of a new transgenic mouse model for assessment of tau gene silencing therapies
Bioluminescence in bigenic tTA/TUL-Y74 mice. a Baseline images of three mice of three different genotypes prior to luciferin injection. b Images of three mice of three different genotypes 10–12 min after luciferin injection. c Graphs of bioluminescence units in bigenic tTA/TUL-Y74 mice that were either given food containing Dox at day 0 or left untreated. The mice were re-injected and re-imaged at 7, 14, 21, and 28 days. Dox treatment produced sustained suppression of bioluminescence