Increased CSF tau level is correlated with decreased lamina cribrosa thickness

Table 1 Subjects’ clinical characteristics

	AD group (n = 18)	Healthy group (n = 26)	P value
Gender (male:female)^a	7:11	12:14	0.760
Age (years)^b	69.7 ± 7.6	63.4 ± 8.0	0.012
Baseline IOP (mmHg)^c	11.5 ± 2.8	12.9 ± 2.5	0.262
SE (D)^c	0.1 ± 2.2	0.7 ± 1.6	0.567
Central corneal thickness (μm)^b	559.6 ± 30.4	572.1 ± 33.6	0.207
Axial length (mm)^b	23.6 ± 1.0	23.8 ± 1.0	0.519
RNFL thickness (μm)^b	102.7 ± 12.1	100.0 ± 12.3	0.474
Total MMSE score^c	19.5 ± 3.7	29.0 ± 1.3	<0.001
BMI (kg/m²)^b	23.9 ± 3.3	23.8 ± 2.4	0.957
Presence of diabetes mellitus^a	3 (16.7 %)	5 (19.2 %)	1.000
Presence of systemic hypertension^a	10 (55.6 %)	9 (34.6 %)	0.222

Data are presented as the mean ± standard deviation unless otherwise specified. Statistically significant values are shown in bold
^aComparisons were made using Fisher’s exact test
^bComparisons were made using an independent-samples t test
^cComparisons were made using a Mann–Whitney U test
AD Alzheimer’s disease, BMI Body mass index, IOP intraocular pressure, MMSE Mini-Mental Status Examination, RNFL retinal nerve fiber layer, SE spherical equivalent

ISSN: 1758-9193