Fig. 1
From: Diagnostic value of cerebrospinal fluid Aβ ratios in preclinical Alzheimer’s disease
Distribution of 18F-flutemetamol SUVRcomp values and ROCs for different CSF analytes. a Distribution of 18F-flutemetamol SUVRcomp values according to age, sex, and APOE genotype. Solid line 1.57 SUVRcomp cutoff value; dashed line 1.57 SUVRcomp cutoff value ±1.5 % corresponding to a test–retest variability for SUVRcomp [20] (1.594 and 1.547). b ROCs for different CSF analytes, with 18F-flutemetamol positivity as classifier. Dots optimal cutoff values for each analyte, corresponding to the highest Youden index. Aβ Amyloid beta, SUVR comp standardized uptake value ratios in composite cortical region, ttau total tau