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Table 3 Comparison of methods versus PIB-PET results

From: Predicting amyloid status in corticobasal syndrome using modified clinical criteria, magnetic resonance imaging and fluorodeoxyglucose positron emission tomography

 

Criteria

FDG-Qual

FDG-Quant

MRI

Number

25

23

22

24

True negative

10

6

7

6

True positive

9

10

9

8

False negative

2

1

1

3

False positive

4

6

5

7

Accuracy

0.76

0.70

0.73

0.58

Rater confidence rating

44%

74%

N/A

54%

  1. Criteria = modified clinical criteria; True Negative = number of patients categorized as fvCBS who were PIB negative; True Positive = number of patients categorized as tpvCBS who were PIB positive; False Negative = number of patients categorized as fvCBS who were PIB positive; False Positive = number of patients categorized as tpvCBS who were PIB negative; Accuracy = True Negative + True Positive/total Number; Confidence Rating = number of highly confident/total number of patients; FDG-Qual, fluorodeoxyglucose PET qualitative (visual assessment); FDG-Quant, fluorodeoxyglucose PET quantitative (computed using ROI); MRI, magnetic resonance imaging; N/A, not applicable; PET, positron emission tomography; ROI, region of interest.