Figure 4From: Fluid biomarkers for diagnosing dementia: rationale and the Canadian Consensus on Diagnosis and Treatment of Dementia recommendations for Canadian physiciansDynamic biomarkers of Alzheimer's disease pathological cascade. The dynamic biomarkers of Alzheimer's disease pathological cascade, as proposed by Jack and collaborators. This model predicts a preclinical and mild cognitive impairment (MCI) stage of Alzheimer's disease (AD) characterized by predominance of amyloid pathology and a dementia phase characterized by amyloid pathology, neurodegenerative changes and subclinical cognitive impairment. Adapted from [4].Back to article page