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Table 1 Challenges of diagnosing dementia in the oldest old

From: Dementia in the oldest old: a multi-factorial and growing public health issue

Challenges

Repercussions

Medical illness, sensory loss (vision/hearing), and physical impairments increasingly contribute to functional decline

Functional impairment is overestimated, leading to overdiagnosis of dementia

Retirement and restricted household responsibilities lead to reduced cognitive demands

Functional impairment is underestimated, leading to underdiagnosis of dementia

Cognitive decline may be considered part of normal aging

Functional impairment is underestimated, leading to underdiagnosis of dementia

Increased likelihood of cognitive impairment in collateral informants of the oldest old compared with the younger old

Functional impairment is underestimated, leading to underdiagnosis of dementia

Lack of normative neuropsychological data

Objective cognitive impairments are overestimated or underestimated, leading to misdiagnosis

Limitations of standard diagnostic criteria

More sensitive for some dementia subtypes, less sensitive for other types