Neuroprotective effects of D-Ala2GIP on Alzheimer's disease biomarkers in an APP/PS1 mouse model

Table 1 Numbers of animals used for analysis of behavioural tasks and of electrophysiological recording of fEPSPs, depending on age, genotype and treatment given

Age	Genotype	Treatment	Behaviour	Electrophysiology
6 months	WT	Saline	N = 14	N = 6
6 months	WT	D-Ala²GIP	N = 14	N = 6
6 months	APP/PS1	Saline	N = 12	N = 8
6 months	APP/PS1	D-Ala²GIP	N = 12	N = 8
12 months	WT	Saline	N = 11	N = 7
12 months	WT	D-Ala²GIP	N = 12	N = 7
12 months	APP/PS1	Saline	N = 11	N = 7
12 months	APP/PS1	D-Ala²GIP	N = 11	N = 6

fEPSP, field excitatory post-synaptic potential; GIP, glucose-dependent insulinotropic polypeptide; N, number.

ISSN: 1758-9193