Figure 3From: Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer's disease Ibero-American cohortEnzyme-linked immunosorbent assays comparing GRN plasma levels between GRN mutation carriers and controls. Measurement of GRN plasma levels for a known GRN mutation (left) and the novel GRN mutation (right), Ile256IlefsX27, observed in our study compared with Alzheimer's disease cases and non-demented older controls. GRN, progranulin; mut, mutant; wt, wild-type.Back to article page