Table 1 Demographic and clinical data of Alzheimer’s disease patients and control subjects

N

70

74

Sex (M/F)

34/36

37/37

Age (y)

73.6 ± 6.6

70.8 ± 9.8

MMSE (score)

20.9 ± 4.2

CDR (score)

1.4 ± 0.7

Disease biomarkers^a

 Aβ_1-42 (pg/mL)

442 (303; 572)

1,034 (608; 1,765)

 Aβ_1-40 (pg/mL)

10,482 (7838; 12,869)

n.a

 T-tau (pg/mL)

673 (464; 965)

176 (93; 325)

 P-tau (pg/mL)

100 (78; 147)

33 (24; 48)

 Aβ_1-42/Aβ_1-40

0.044 (0.038; 0.051)

n.a

 Aβ_1-42/T-tau

0.67 (0.36; 1.09)

6.40 (2.01; 14.53)

 Aβ_1-42/P-tau

4.4 (2.5; 6.3)

30.34 (13.78; 53.13)

Apolipoprotein E genotype (N, %)^b

 E4/E4

4 (5.8)

2 (5.9)

 E3/E4

30 (43.5)

4 (11.8)

 E3/E3

33 (47.8)

25 (73.5)

 E2/E3

2 (2.9)

3 (8.8)

Statins (N, %)

19 (27.1)

5 (6.8)