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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Could tau-PET imaging contribute to a better understanding of the different patterns of clinical progression in Alzheimer’s disease? A 2-year longitudinal study

Fig. 5

Relations of tau SUVr progression with cognitive decline. Results of the voxelwise analyses that show the association between the evolutions of the 4 cognitive outcomes over 2 years: MMSE, memory score, instrumental score and executive score and the evolution of the tau SUVr values AB in the whole AD group (negative t values in A, representing the regions where the increase in SUVr values is associated with the decrease in cognitive scores, and positive t values in B, representing the regions where the decrease in SUVr values is associated with the decrease in cognitive scores), and C in the low-Tau1 AD subgroup (projection on the 3D MRI MNI template). RFT-based multiple comparison correction with a clusterwise threshold of p < 0.001 and a cluster-forming threshold of p < 0.001

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