Fig. 1
Development of Aβ pathology in AppNL−G−F mice over time. A Schematic image of sequential brain extraction. B ELISA quantification of soluble Aβ aggregates in TBS brain (cortex) extract centrifuged at 100,000 × g (TBS 100 K) from AppNL−G−F mice of different ages. C. ELISA quantification of Aβ aggregates in TBS brain extracts centrifuged at 16,000 × g (TBS 16 K) and of Aβ1-42 in FA extracts D of the cortex, hippocampus, and cerebellum of AppNL−G−F mice at different ages. A was created with BioRender