Fig. 2
From: Tau accumulation in autosomal dominant Alzheimer’s disease: a longitudinal [18F]flortaucipir study
FTP signal uptake against EYO. Observed values of FTP uptake in all 5 ROIs (A entorhinal, B meta temporal, C composite global, D posterior cingulate, E precuneus) against EYO. Symptomatic mutation carriers are represented in red, presymptomatic carriers in blue, and non-carriers in black. Those measurements that belong to the same individual are connected by a line. To maintain blinding of mutation status, the values of the x-axis for all EYO plots have been removed except for EYO = 0, indicated by a broken line, plus an approximate indication of EYO = −10; additionally, four asymptomatic individuals with an EYO > 10 are also not shown (but these data were included in all analyses)