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Table 6 Results of linear regression analyses testing the association between epigenetic age acceleration and AD using the HMTP and CorCL DNAm age estimators

From: Entorhinal cortex epigenome-wide association study highlights four novel loci showing differential methylation in Alzheimer’s disease

Model

Effect (β)

p-value

AD Status ~ ageaccelHMTP + sex

0.10

5.74E-05

Braak stage ~ ageaccelHMTP + sex

0.07

1.96E-04

AD Status ~ ageaccelCorCL + sex

0.17

2.72E-05

Braak stage ~ ageaccelCorCL + sex

0.11

7.51E-05

  1. β: Effect sizes of AD case–control status / Braak stage with HMTP / CorCL age acceleration
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Alzheimer's Research & Therapy

ISSN: 1758-9193