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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Entorhinal cortex epigenome-wide association study highlights four novel loci showing differential methylation in Alzheimer’s disease

Fig. 2

Manhattan plot for the EWAS meta-analysis using Braak staging across three EC datasets. The red line indicates the experiment-wide significance threshold of 1.64E-07, whereas the purple line indicates the suggestive significance threshold of 1.00E-05. CpGs with experiment-wide significant association are marked in red and annotated with the gene name according to the Illumina manifest (v1.0 B5). The CpG around DIRAS1 is novel

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Alzheimer's Research & Therapy

ISSN: 1758-9193