Skip to main content

Table 2 Results of multiple regression analyses with cognitive test performance over five tests as the dependent variable and years to estimated clinical onset (YECO and YECO2) and years of education as independent variables in adAD mutation carriers. Significant values are bolded. Note that results of performance are given as raw scores (the higher the better) for all tests

From: A biomarker-validated time scale in years of disease progression has identified early- and late-onset subgroups in sporadic Alzheimer’s disease

Test

rmult

r2

F

df

p

β (Y)

β (Y2)

β (educ)

Similarities

0.67

0.45

9.35

3/35

 < 0.001

 − 0.955***

 − 0.540*

 + 0.211 ns

Block Design

0.78

0.61

19.13

3/36

 < 0.001

 − 1.034***

 − 0.447*

 + 0.219*

RAVL learning

0.81

0.66

21.25

3/33

 < 0.001

 − 1.022***

 − 0.399 ns

 + 0.218*

RO retention

0.75

0.56

13.38

3/32

 < 0.001

 − 0.945***

 − 0.229 ns

 − 0.010 ns

Digit Symbol

0.82

0.68

24.27

3/35

 < 0.001

 − 0.894***

 − 0.328 ns

 + 0.311**

  1. ns, not significant; RAVL, Rey auditory verbal learning; RO, Rey-Osterrieth
  2. * p < 0.05; ** p<0.01; *** p < 0.001