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Fig. 6 | Alzheimer's Research & Therapy

Fig. 6

From: Five-mer peptides prevent short-term spatial memory deficits in Aβ25-35-induced Alzheimer’s model mouse by suppressing Aβ25-35 aggregation and resolving its aggregate form

Fig. 6

Resolving effects of GSGFK and GSGNR on aggregated Aβ25-35. Aβ25-35 (100 μM) was pre-incubated for 4 h to make its aggregated form, AgAβ25-35. a Time course of ThT-fluorescence intensity. b The decreasing ratio of the fluorescence intensity at 4 h. Decreasing ratio was calculated by measuring the fluorescence intensity at 0 and 4 h using the following formula: Decreasing ratio = fluorescence intensity at 0 h − fluorescence intensity at 4 h / fluorescence intensity at 0 h × 100. Data shown are mean ± standard error of the mean (n = 3), versus Aβ25-35 group. *p < 0.05. a GSGNR, p = 0.008; GSGFK, p = 0.002; b GSGNR, p = 0.014; GSGFK, p = 0.018

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Alzheimer's Research & Therapy

ISSN: 1758-9193