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Table 4 Regions showing relative CBF changes in patients with AD compared to NCs after adjusting for global value (ANCOVA normalization)

From: The identification and cognitive correlation of perfusion patterns measured with arterial spin labeling MRI in Alzheimer’s disease

Structure

BA

X

Y

Z

T

Cluster size (ml)

Decreased CBF

 Bilateral posterior cingulate

23, 31

 − 2

 − 48

32

7.1

11.5

 Bilateral middle cingulate

23

2

 − 33

41

5.5

a

 Bilateral precuneus

7

3

 − 66

44

7.4

a

 Right inferior parietal lobule

39, 40

53

 − 41

51

5.9

4.0

 Right inferior temporal gyrus

20

59

 − 44

 − 15

5.3

0.6

 Left inferior parietal lobule

7, 40

 − 45

 − 51

47

7.0

9.1

 Left inferior temporal gyrus

20, 37

 − 56

 − 42

 − 20

6.0

1.3

Increased CBF

 Right parietal postcentral gyrus

43

59

 − 6

23

7.3

7.8

 Right frontal precentral gyrus

4, 6

38

 − 18

57

7.5

a

 Right frontal supplementary motor area

6

9

3

53

6.3

1.2

 Left frontal precentral gyrus

4, 6

 − 53

3

24

5.6

0.5

 Right putamen

 

32

2

0

6.0

1.2

  1. Significant clusters were defined using an FWE correction at P < 0.05
  2. BA Brodmann area
  3. aRegion belongs to the cluster for which the volume is provided above