The identification and cognitive correlation of perfusion patterns measured with arterial spin labeling MRI in Alzheimer’s disease

Table 2 Regions involved in topographies of ADRP

Structure	BA	X	Y	Z	T value	Cluster size (ml)
Negative loading
Bilateral middle cingulate^a	23, 31	2	− 47	33	3.4	260.9
Bilateral precuneus^a	7, 39, 40	2	− 63	36	3.0	^b
Right middle frontal gyrus	8, 9	39	23	38	1.5	13.7
Left middle frontal gyrus	8, 9	− 29	35	38	1.7	12.7
Left cerebellum		− 21	− 77	− 23	1.3	3.7
Positive loading
Right superior frontal gyrus	11	3	60	− 28	2.1	149.9
Right frontal orbital gyrus	11	6	54	− 33	2.0	^b
Left frontal rectal gyrus	11	− 3	55	− 31	2.0	^b

The coordinates were reliable at P < 0.001 based on the bootstrapping algorithm. Cluster size > 100
ADRP AD-related perfusion pattern, BA Brodmann area
^aThis region extends to and involves the bilateral posteior cingulate and inferior parietal lobule according to the overlapped map
^bRegion belongs to the cluster for which the size is provided above

ISSN: 1758-9193