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Table 5 Top 10 most significant DMRs associated with CSF phosphorylated tau181 (pTau181) in cognitively normal (CN) subjects and Alzheimer’s disease (AD) subjects. For each DMR, annotations include the location of the DMR based on hg19/GRCh37 genomic annotation (chr, start, end), and nearby genes based on GREAT (GREAT_annotation). Direction indicates a positive or negative association between DNA methylation at a CpG located within the DMR and CSF biomarker. Highlighted in red are gene promoter regions mapped to significant DMRs

From: Distinct CSF biomarker-associated DNA methylation in Alzheimer’s disease and cognitively normal subjects