Fig. 4
Plasma GFAP and plasma Aβ1-42/1–40 concentrations in cognitively unimpaired volunteers stratified by APOE ε4 gene dose. Differences in biomarker concentrations between APOE ε4 gene doses, correlations with cortical composite amyloid PET standardized uptake value ratios (SUVRs), and TSPO PET distribution volume ratios (DVRs) for A plasma glial fibrillary acidic protein (GFAP) and B plasma Aβ1-42/1–40. Differences between groups were tested with Kruskal–Wallis with Dunn's method for multiple comparisons, and correlations with Spearman’s rank correlation