Fig. 2

Group comparisons of TBSS between patients with FTLD and cognitively unimpaired. Left: Regions where fractional anisotropy values in the FTLD subtypes are considerably lower than in cognitively unimpaired within the white matter skeleton (green) are reported on a light blue–blue scale (0.05 < P < 0.005). Right: Regions where mean diffusivity values in the FTLD subtype are considerably higher than in cognitively unimpaired within the white matter skeleton (green) are reported on a red–orange scale (0.05 < P < 0.005). The results have been overlaid on a skull-stripped MNI152 template. bvFTD, behavioral variant of frontotemporal dementia; CU, cognitively unimpaired nfvPPA, nonfluent variant primary progressive aphasia; svPPA, semantic variant primary progressive aphasia; TBSS, tract-based spatial statistics