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Table 3 Comparison between the Controls and post-COVID-19 groups on demographics, reference CNB and SCD-T

From: Validation study of “Santé-Cerveau”, a digital tool for early cognitive changes identification

 

Controls

N = 65 (82.27%)

Post-COVID-19

N = 14

(17.72%)

p

Demographics

 Age, years old

69.91 ± 4.86

45.07 ± 11.36

 < 0.001*

Gender (Female)

44 (67.69%)

11 (78.57%)

0.333

 Educational level

   

   ≤ 12 years

9 (13.85%)

4 (28.5%)

0.082

  between 13 and 17 years

32 (49.23%)

3 (18.8%)

 

   ≥ 17 years

24 (36.92%)

7 (50%)

 

Reference NCB

 MMSE

66.36 ± 4.83

51.78 ± 10.11

 < 0.001*

 FAB

1.36 ± 0.97

-0.69 ± 1.86

 < 0.001*

 FCSRT free recall+

0.83 ± 0.92

-0.18 ± 1.71

0.047*

 FCSRT total recall +

0.49 ± 0.51

-0.32 ± 1.37

0.0076*

SCD-T

 5-WT total score °

-0.52 ± 1.8

-0.68 ± 2.67

0.032*

 5-WT weighted total score °

0.23 ± 1.05

-0.95 ± 1.8

0.0082*

 TMT A time, seconds #

-1.28 ± 0.75

-0.42 ± 0.77

 < 0.001*

 TMT B time, seconds #

-1.29 ± 0.44

-0.55 ± 0.92

 < 0.001*

 TMT B-A, time, seconds#

-1.09 ± 0.55

-0.36 ± 0.82

 < 0.001*

 NCT good answers ×

6.32 ± 1.89

3.57 ± 1.69

 < 0.001*

  1. Data are presented using mean ± standard deviation (SD) for quantitative measures and using number (percentage relative to group)
  2. NCT Number Coding Test; FAB Frontal Assessment Battery; FCSRT Free and Cued Selective Reminding Test; 5-WT five-word test; MMSE Mini-Mental State Examination; CNB Comprehensive Neuropsychological Battery; SCD-T Santé-Cerveau digital tool; TMT Trail Making Test
  3. : for categorical and continuous measures, group effect was tested using Mann-Whithney U test
  4. #: z-scores computed using GREFEX 2008 norms
  5. °: z-scores computed using Croisile et al. 2007 norms
  6. : T-scores computed using Folstein et al. 2002 norms
  7. +: z-scores computed using norms provided by neuropsychologists of the IM2A
  8. : z-scores computed using Appollonio et al. 2004 norms
  9. ×: standard scores computed using WAIS IV