All dementia | Apoe4 ε + | Apoe4ε- | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Factor 1 | Factor 2 | N | rho (95% CI) | p-value | N | rho (95% CI) | p-value | N | rho (95% CI) | p-value |
CSF ApoA1 | CSF ICAM1 | 50 | 0.55 (0.32, 0.72) | < 0.001 | 36 | 0.64 (0.40, 0.80) | < 0.001 | 14 | 0.39 (− 0.18, 0.76) | 0.18 |
CSF VCAM1 | 50 | 0.62 (0.41, 0.77) | < 0.001 | 36 | 0.64 (0.40, 0.80) | < 0.001 | 14 | 0.57 (0.06, 0.85) | 0.030 | |
Plasma ICAM1 | 50 | 0.04 (− 0.24, 0.31) | 0.79 | 36 | 0.18 (− 0.16, 0.48) | 0.29 | 14 | − 0.31 (− 0.72, 0.27) | 0.30 | |
Plasma MMP9 | 50 | 0.07 (− 0.22, 0.34) | 0.65 | 36 | − 0.02 (− 0.35, 0.31) | 0.90 | 14 | 0.29 (− 0.29, 0.71) | 0.33 | |
Plasma VCAM1 | 50 | 0.07 (− 0.21, 0.34) | 0.63 | 36 | 0.06 (− 0.27, 0.38) | 0.73 | 14 | 0.09 (− 0.46, 0.59) | 0.76 | |
Plasma ApoA1 | CSF ICAM1 | 50 | − 0.02 (− 0.29, 0.26) | 0.90 | 36 | − 0.02 (− 0.34, 0.31) | 0.93 | 14 | − 0.02 (− 0.55, 0.52) | 0.94 |
CSF VCAM1 | 50 | − 0.02 (− 0.30, 0.26) | 0.89 | 36 | 0.02 (− 0.31, 0.35) | 0.89 | 14 | − 0.19 (− 0.65, 0.38) | 0.52 | |
Plasma ICAM1 | 50 | − 0.15 (− 0.41, 0.14) | 0.31 | 36 | − 0.14 (− 0.45, 0.20) | 0.41 | 14 | − 0.19 (− 0.65, 0.38) | 0.52 | |
Plasma MMP9 | 50 | 0.14 (− 0.15, 0.40) | 0.34 | 36 | 0.14 (− 0.20, 0.45) | 0.42 | 14 | 0.11 (− 0.44, 0.61) | 0.70 | |
Plasma VCAM1 | 50 | 0.07 (− 0.21, 0.34) | 0.63 | 36 | 0.15 (− 0.19, 0.46) | 0.38 | 14 | − 0.20 (− 0.66, 0.37) | 0.50 | |
TG/HDL | CSF ICAM1 | 50 | − 0.00 (− 0.28, 0.28) | 0.98 | 36 | − 0.07 (− 0.39, 0.26) | 0.67 | 14 | 0.11 (− 0.45, 0.61) | 0.71 |
CSF VCAM1 | 50 | − 0.09 (− 0.36, 0.19) | 0.51 | 36 | − 0.17 (− 0.47, 0.17) | 0.33 | 14 | 0.06 (− 0.49, 0.57) | 0.85 | |
Plasma ICAM1 | 50 | 0.30 (0.02, 0.53) | 0.036 | 36 | 0.28 (− 0.05, 0.56) | 0.097 | 14 | 0.34 (− 0.23, 0.74) | 0.24 | |
Plasma MMP9 | 50 | − 0.20 (− 0.45, 0.09) | 0.18 | 36 | − 0.10 (− 0.41, 0.24) | 0.57 | 14 | − 0.43 (− 0.78, 0.13) | 0.13 | |
Plasma VCAM1 | 50 | 0.01 (− 0.27, 0.29) | 0.95 | 36 | − 0.13 (− 0.44, 0.20) | 0.44 | 14 | 0.39 (− 0.18, 0.76) | 0.17 |