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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Attenuation of Alzheimer’s brain pathology in 5XFAD mice by PTH1-34, a peptide of parathyroid hormone

Fig. 5

PTH1-34 diminishment of brain inflammation in 5XFAD mice. A Real-time PCR (RT-PCR) analysis of indicated gene expressions in the cortex of 6 ~ MO WT and 5XFAD female mice with PTH1-34 or Veh treatment. The level of GAPDH was normalized to 1, n = 3 per group. B Total quantification of relative gene expression levels in A. The level of WT group was normalized to 1, n = 10 gene per group. C The summary of altered genes in the 5XFAD-PTH1-34 treatment group compared with the 5XFAD-Veh group in cortex. D RT-PCR analysis of indicated gene expressions in the hippocampus of 6 ~ MO female mice, n = 3 per group. E Total quantification of relative gene expression levels in D. F The summary of altered genes in the 5XFAD-PTH1-34 treatment group compared with the 5XFAD-Veh group in hippocampus. All quantification data were presented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, one-way ANOVA with Tukey’s multiple-comparison test was used

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