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Table 3 Characteristics of the patients with CSVD in CDR 0, 0.5, and 1–2

From: Changes in CSF sPDGFRβ level and their association with blood–brain barrier breakdown in Alzheimer’s disease with or without small cerebrovascular lesions

 

Score

CDR 0 (N = 27)

CDR 0.5 (N = 48)

CDR 1–2 (N = 83)

p value

CSVD, n (%)

0

20 (74.07%)

30 (62.50%)

25 (30.12%)

< 0.001

1

6 (22.22%)

8 (16.67%)

25 (30.12%)

 

≥ 2

1 (3.70%)

10 (20.83%)

33 (39.76%)

 

PVWMH, n (%)

0

22 (81.48%)

24 (50.00%)

26 (31.33%)

< 0.001

1

5 (18.52%)

17 (35.42%)

29 (34.94%)

 

2

0 (0.00%)

6 (12.50%)

22 (26.51%)

 

3

0 (0.00%)

1 (2.08%)

6 (7.23%)

 

DWMH, n (%)

0

23 (85.19%)

30 (62.50%)

42 (50.60%)

0.035

1

4 (14.81%)

17 (35.42%)

32 (38.55%)

 

2

0 (0.00%)

1 (2.08%)

6 (7.23%)

 

3

0 (0.00%)

0 (0.00%)

3 (3.61%)

 

CMBn, median (IQR)

 

0 ± 0

0 ± 0

0 ± 4

0.028

  1. p < 0.05 was considered statistically significant.
  2. PVWMHs periventricular spaces white matter hyperintensity Fazekas score, DWMHs deep spaces white matter hyperintensity Fazekas score, CMBn cerebral microbleeds numbers