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Table 2 Descriptive statistics of neuropsychological data

From: Shared and unique effects of ApoEε4 and pathogenic gene mutation on cognition and imaging in preclinical familial Alzheimer’s disease

Domain

Neuropsychological test

Subscale score

Controla

(n = 76)

APOEε4

(n = 26)

APP

(n = 17)

PS1

(n = 20)

Episode memory

AVLTa

Immediate 1

7.07 (2.68)

6.86 (2.17)

8.18 (2.13)

7.05 (1.43)

Immediate 2

9.84 (2.67)

10.14 (2.53)

11.41 (1.84)

10.53 (1.62)

Immediate 3

12.16 (2.25)

11.91 (2.33)

13.41 (1.73)

12.32 (1.80)

Immediate total

28.93 (6.40)

28.86 (6.22)

33.12 (4.73)

29.89 (3.31)

Delayed recall

10.87 (3.00)

11.59 (2.65)

13.12 (1.58)#

11.21 (2.32)

Cued recall

10.49 (4.30)

10.50 (4.78)

13.59 (2.58)**

11.11 (3.68)

Delayed recognition

12.73 (2.47)

13.05 (1.62)

14.06 (1.09)

12.42 (3.20)

ROCFb

Figure copy

34.97 (3.11)

35.30 (1.61)

35.82 (0.53)

35.78 (0.55)

Figure recall

21.14 (7.38)

21.14 (6.35)

21.12 (7.22)

21.03 (6.91)

Working memory

Digit Span

Forward

8.57 (1.21)

8.82 (1.22)

9.00 (0.61)

8.47 (1.07)

Backward

5.85 (1.64)

6.05 (1.89)

6.24 (1.15)

5.79 (1.65)

Language

BNTc

Initial naming

26.25 (3.07)

27.36 (2.40)

27.12 (1.93)

25.58 (2.59)

Cued naming

0.64 (0.98)

0.55 (0.96)

0.59 (1.50)

0.58 (0.77)

Selective naming

2.73 (2.73)

1.77 (1.60)

2.35 (1.41)

3.32 (1.97)

Visuospatial perception

TMTd A

Time (s)

37.66 (15.70)

36.23 (15.98)

33.18 (17.96)

30.36 (16.47)

Correct trails

24.09 (1.26)

23.95 (0.21)

24.00 (0.00)

24.05 (0.23)

Executive function

TMT B

Time (s)

64.01 (38.89)

64.50 (37.51)

46.06 (17.05)

48.74 (26.90)

Correct trails

23.55 (1.62)

23.09 (2.65)

24.00 (0.00)

24.05 (0.23)

  1. #0.017 < P < 0.1, *0.01 < P < 0.017, **0.001 < P < 0.01
  2. aAVLT: Auditory Verbal Learning Test
  3. bROCF: Rey-Osterrieth complex figure test
  4. cBNT: Boston naming test
  5. dTMT: trail making test