Skip to main content
Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Comparison of ultrasensitive and mass spectrometry quantification of blood-based amyloid biomarkers for Alzheimer’s disease diagnosis in a memory clinic cohort

Fig. 3

Performance of the plasma amyloid biomarkers to discriminate AD from other clinical diagnoses. A Receiver operating characteristic (ROC) analysis adjusted for age and APOE ε4 status of Simoa Aβ42/40, IPMS-Shim Aβ42/40, and composite biomarkers between AD and MCI groups. B ROC analysis of the three plasma amyloid biomarkers between AD and SCI groups. C ROC analysis of the biomarkers between AD and NDD groups. D ROC analysis of the biomarkers between AD and OND groups. AUC (area under the curve) is presented with 95% confidence interval (CI). The best values for sensitivity (se) and specificity (sp) were computed at an optimal cutoff point determined using Youden’s index

Back to article page

Alzheimer's Research & Therapy

ISSN: 1758-9193