Fig. 2
Levels of amyloid plasma biomarkers measured by Simoa-3PLEX and according to diagnosis. A Simoa Aβ42/40 ratio is not significantly different between diagnoses. B The Aβ42/40 ratio is globally different between groups when measured with Simoa but associated with an effect of age only. Plasma cutoff for Simoa-Aβ42/40, 0.054, is represented with dashed lines. Results are boxplot, and mean ± SD are indicated below, n = 12–73. ANCOVA with diagnosis, age, and APOE ε4 status as factors followed by multiple comparisons of means using Tukey contrasts and diagnosis as a factor